Reactivity of colon cancer artery to vasoconstrictive medium
2014
The invention discloses the reactivity of a colon cancer artery to a vasoconstrictive medium. An alpha receptor and an ETA receptor are main vasoconstrictive receptors of a normal artery, and the vasoconstrictive action of the alpha receptor and the ETA receptor of the colon cancer artery is obviously weaker than that of a cancer peripheral artery. The maximal contraction and the half-maximal effect concentration of normal artery contraction caused by noradrenaline (NA) are respectively 97%+/-19% and 5.94+/-0.17, Emax and pEC50 of the NA contraction of the colon cancer artery are respectively 74%+/-5% and 5.54+/-0.21, and Emax and pEC50 of the contraction of the cancer peripheral artery are respectively 119%+/-11% and 5.84+/-0.09.
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