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Jeffrey J. Heard

University of California, Los Angeles

4

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An oncogenic mutant of RHEB, RHEB Y35N, exhibits an altered interaction with BRAF resulting in cancer transformation

2018 BMC Cancer
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Abstract A09: Therapeutic targeting of TSC2-deficient cells with Methotrexate: Results of a drug repurposing screen

2017 Clinical Cancer Research
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Rheb protein binds CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamoylase, and dihydroorotase) protein in a GTP- and effector domain-dependent manner and influences its cellular localization and carbamoyl-phosphate synthetase (CPSase) activity.

2015 Journal of Biological Chemistry
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Recent progress in the study of the Rheb family GTPases

2014 Cellular Signalling
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Citations (43)