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Murali Rajagopalan
Murali Rajagopalan
Schering-Plough
Amyloid precursor protein secretase
Biochemistry
Chemistry
Enzyme inhibitor
Chemical synthesis
4
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89
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Novel orally active morpholine N-arylsulfonamides γ-secretase inhibitors with low CYP 3A4 liability
2009
Bioorganic & Medicinal Chemistry Letters
Hubert B. Josien
Thomas A. Bara
Murali Rajagopalan
John W. Clader
William J. Greenlee
Leonard Favreau
Lynn A. Hyde
Amin A. Nomeir
Eric M. Parker
Lixin Song
Lili Zhang
Qi Zhang
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Citations (15)
Discovery of 2,4,6-trisubstituted N-arylsulfonyl piperidines as γ-secretase inhibitors
2007
Bioorganic & Medicinal Chemistry Letters
Hongmei Li
Theodros Asberom
Thomas A. Bara
John W. Clader
William J. Greenlee
Hubert B. Josien
Mark D. McBriar
Amin A. Nomeir
Dmitri A. Pissarnitski
Murali Rajagopalan
Ruo Xu
Zhiqiang Zhao
Lixin Song
Lili Zhang
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Citations (22)
Small conformationally restricted piperidine N-arylsulfonamides as orally active γ-secretase inhibitors
2007
Bioorganic & Medicinal Chemistry Letters
Hubert B. Josien
Thomas A. Bara
Murali Rajagopalan
Theodros Asberom
John W. Clader
Leonard Favreau
William J. Greenlee
Lynn A. Hyde
Amin A. Nomeir
Eric M. Parker
Dmitri A. Pissarnitski
Lixin Song
Gwendolyn T. Wong
Lili Zhang
Qi Zhang
Zhiqiang Zhao
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Citations (23)
Discovery of γ-secretase inhibitors efficacious in a transgenic animal model of Alzheimer's disease
2007
Bioorganic & Medicinal Chemistry Letters
Theodros Asberom
Zhiqiang Zhao
Thomas A. Bara
John W. Clader
William J. Greenlee
Lynn A. Hyde
Hubert B. Josien
Wei Li
Andrew T. McPhail
Amin A. Nomeir
Eric M. Parker
Murali Rajagopalan
Lixin Song
Gwendolyn T. Wong
Lili Zhang
Qi Zhang
Dmitri A. Pissarnitski
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Citations (29)
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