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Mi Chen
Mi Chen
Neurocrine Biosciences
Chemistry
Biochemistry
Stereochemistry
Carboxylic acid
Chemical synthesis
4
Papers
115
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Zwitterionic uracil derivatives as potent GnRH receptor antagonists with improved pharmaceutical properties.
2008
Bioorganic & Medicinal Chemistry Letters
Colin F. Regan
Zhiqiang Guo
Yongsheng Chen
Charles Q. Huang
Mi Chen
Wanlong Jiang
Jaimie K. Rueter
Timothy Coon
Chen Chen
John Saunders
Michael S. Brown
Steve F. Betz
R. Scott Struthers
Chun Yang
Jenny Wen
Ajay Madan
Yun-Fei Zhu
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Citations (22)
Discovery of Sodium R-(+)-4-{2-[5-(2-Fluoro-3-methoxyphenyl)-3-(2-fluoro-6-[trifluoromethyl]benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenylethylamino}butyrate (Elagolix), a Potent and Orally Available Nonpeptide Antagonist of the Human Gonadotropin-Releasing Hormone Receptor
2008
Journal of Medicinal Chemistry
Chen Chen
Dongpei Wu
Zhiqiang Guo
Qiu Xie
Greg J. Reinhart
Ajay Madan
Jenny Wen
Takung Chen
Charles Q. Huang
Mi Chen
Yongsheng Chen
Fabio C. Tucci
Martin W. Rowbottom
Joseph Pontillo
Yun-Fei Zhu
Warren Wade
John Saunders
Haig Bozigian
R. Scott Struthers
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Citations (83)
Receptor antagonists of gonadotropin releasing hormone and methods related thereto
2008
Graham Beaton
Mi Chen
Timothy Coon
Todd Ewing
Wanlong Jiang
Richard Lowe
Willy Moree
Nicole Harriott
Warren Wade
Liren Zhao
Yun-Fei Zhu
Martin W. Rowbottom
Neil J. Ashweek
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Identification of 2-(4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-3-yl)-ethylamine derivatives as novel GnRH receptor antagonists
2007
Bioorganic & Medicinal Chemistry Letters
Mi Chen
Zhiqiang Guo
Marion Lanier
Liren Zhao
Stephen F. Betz
Charles Q. Huang
Colin J. Loweth
Neil J. Ashweek
Xin-Jun Liu
R. Scott Struthers
Margaret J. Bradbury
James W. Behan
Jenny Wen
Zhihong O'Brien
John Saunders
Yun-Fei Zhu
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Citations (10)
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