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Roland Frötschl

Federal Institute for Drugs and Medical Devices

21

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The EU Response to the Presence of Nitrosamine Impurities in Medicines

2021 Frontiers of Medicine in China
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N-Nitrosodimethylamine-Contaminated Valsartan and the Risk of Cancer—A Longitudinal Cohort Study Based on German Health Insurance Data.

2021 Deutsches Arzteblatt International
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Do Carcinogens Have a Threshold Dose? The Pros and Cons

2021
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TGx-DDI, a Transcriptomic Biomarker for Genotoxicity Hazard Assessment of Pharmaceuticals and Environmental Chemicals

2019
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Targets and mechanisms of chemically induced aneuploidy. Part 1 of the report of the 2017 IWGT workgroup on assessing the risk of aneugens for carcinogenesis and hereditary diseases

2019 Mutation Research-genetic Toxicology and Environmental Mutagenesis
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The rat bone marrow micronucleus test: Statistical considerations on historical negative control data

2019 Regulatory Toxicology and Pharmacology
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Inhibition of the PI3K but not the MEK/ERK pathway sensitizes human glioma cells to alkylating drugs

2018 Cancer Cell International
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Development and validation of a high-throughput transcriptomic biomarker to address 21st century genetic toxicology needs

2017 Proceedings of the National Academy of Sciences of the United States of America
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Time-matched analysis of DNA adduct formation and early gene expression as predictive tool for renal carcinogenesis in methylazoxymethanol acetate treated Eker rats

2017 Archives of Toxicology
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Cisplatin resistance in non-small cell lung cancer cells is associated with an abrogation of cisplatin-induced G2/M cell cycle arrest

2017 PLOS ONE
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