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Nils Brünner

University of Copenhagen

384

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12202

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A Comprehensive RNA Study to Identify circRNA and miRNA Biomarkers for Docetaxel Resistance in Breast Cancer

2021 Frontiers in Oncology
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Abstract PS17-43: Sco-101 is a novel oral drug that reverses antiestrogen resistance in breast cancer cells

2021 Cancer Research
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New use for old drugs: Epirubicin in colorectal cancer.

2021 Acta Oncologica
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Four phase 1 trials to evaluate the safety and pharmacokinetic profile of single and repeated dosing of SCO‐101 in adult male and female volunteers

2020 Basic & Clinical Pharmacology & Toxicology
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Abstract CT264: Clinical phase II study of SCO-101 - an inhibitor of SRPK1 and ABCG2 - restoring sensitivity to FOLFIRI in metastatic FOLFIRI resistant colorectal cancer patients

2020 Tumor Biology
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Characterization of resistance to a recombinant hexameric Fas-ligand (APO010) in human cancer cell lines

2020 Experimental Hematology
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605TiP Targeting anti-cancer drug resistance in gastro-intestinal cancer: Inhibition of the SRPK1 kinase and degradation of the ABCG2 drug efflux pump

2020 Annals of Oncology
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The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP

2020 Cells
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ABCG2 Protein Levels and Association to Response to First-Line Irinotecan-Based Therapy for Patients with Metastatic Colorectal Cancer.

2020 International Journal of Molecular Sciences
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Pharmacodynamic modelling reveals synergistic interaction between docetaxel and SCO-101 in a docetaxel-resistant triple negative breast cancer cell line.

2020 European Journal of Pharmaceutical Sciences
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