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Philip A. Cole

Johns Hopkins University School of Medicine
Harvard University
University of Alabama at Birmingham

510

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29444

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p300 suppresses the transition of myelodysplastic syndromes to acute myeloid leukemia.

2021 JCI insight
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Site-Specific 5-Formyl Cytosine Mediated DNA-Histone Cross-Links: Synthesis and Polymerase Bypass by Human DNA Polymerase η.

2021 Angewandte Chemie
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The regulatory enzymes and protein substrates for the lysine β-hydroxybutyrylation pathway

2021 Science Advances
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N-Terminal Protein Labeling with N-Hydroxysuccinimide Esters and Microscale Thermophoresis Measurements of Protein-Protein Interactions Using Labeled Protein.

2021
- Hanjie Jiang
- Philip A. Cole
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The structural basis of PTEN regulation by multi-site phosphorylation.

2021 Nature Structural & Molecular Biology
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Ubiquitin Ligase Activities of WWP1 Germline Variants K740N and N745S.

2021 Biochemistry
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Chemical Screen Identifies Diverse and Novel Histone Deacetylase Inhibitors as Repressors of NUT Function: Implications for NUT Carcinoma Pathogenesis and Treatment.

2021 Molecular Cancer Research
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Epigenetic Silencing of BMP6 by the SIN3A-HDAC1/2 Repressor Complex Drives Melanoma Metastasis via FAM83G/PAWS1.

2021 Molecular Cancer Research
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HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury.

2021 Scientific Reports
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Discovery of Spirohydantoins as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases.

2021 Bioorganic & Medicinal Chemistry Letters
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Citations (2)