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Peter C. Isakson

G. D. Searle & Company

68

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1,2-Diarylimidazoles as Potent, Cyclooxygenase-2 Selective, and Orally Active Antiinflammatory Agents.

2010 ChemInform
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Characterization of Celecoxib and Valdecoxib Binding to Cyclooxygenase

2003 Molecular Pharmacology
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Neuronal overexpression of COX-2 results in dominant production of PGE2 and altered fever response

2003 Neuromolecular Medicine
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Biochemical and clinical evidence that aspirin-intolerant asthmatic subjects tolerate the cyclooxygenase 2-selective analgetic drug celecoxib☆☆☆★

2003 The Journal of Allergy and Clinical Immunology
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Pharmacology of Celecoxib in Rat Brain after Kainate Administration

2002 Journal of Pharmacology and Experimental Therapeutics
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Cox-2-specific inhibitors: definition of a new therapeutic concept.

2001 American Journal of Therapeutics
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Effects of Celecoxib, a Novel Cyclooxygenase‐2 Inhibitor, on Platelet Function in Healthy Adults: A Randomized, Controlled Trial

2000 The Journal of Clinical Pharmacology
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A proposed three step mechanism for inhibition of cyclooxygenase-2

1999 Prostaglandins & Other Lipid Mediators
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Treatment of Osteoarthritis With Celecoxib, a Cyclooxygenase-2 Inhibitor: A Randomized Controlled Trial

1999 Mayo Clinic Proceedings
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Cyclooxygenase-2 (COX-2) Plays a Significant Role in Regulating the Fetal Ductus Asteriosus In Vivo and In Vitro

1999 Pediatric Research
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