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Fergus E. Poynton

Trinity College, Dublin

15

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522

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Understanding the factors controlling the photo-oxidation of natural DNA by enantiomerically pure intercalating ruthenium polypyridyl complexes through TA/TRIR studies with polydeoxynucleotides and mixed sequence oligodeoxynucleotides

2020 Chemical Science
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Nanotechnology based therapeutics for lung disease

2019 Thorax
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The development of ruthenium(II) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications

2017 Chemical Society Reviews
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Inosine can increase DNA's susceptibility to photo-oxidation by a Ru(II) complex due to structural change in the minor groove

2017 Chemistry: A European Journal
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DNA Structure and Dynamics - A Combinational Approach

2016 Acta Crystallographica Section A
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Direct observation by time-resolved infrared spectroscopy of the bright and the dark excited states of the [Ru(phen) 2 (dppz)] 2+ light-switch compound in solution and when bound to DNA

2016 Chemical Science
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Reversal of a Single Base‐Pair Step Controls Guanine Photo‐Oxidation by an Intercalating Ruthenium(II) Dipyridophenazine Complex

2015 Angewandte Chemie
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Unexpected DNA binding properties with correlated downstream biological applications in mono vs. bis-1,8-naphthalimide Ru(II)-polypyridyl conjugates

2015 Dalton Transactions
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Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy

2015 Nature Chemistry
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Monitoring guanine photo-oxidation by enantiomerically resolved Ru(II) dipyridophenazine complexes using inosine-substituted oligonucleotides.

2015 Faraday Discussions
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