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Xin Cai
Xin Cai
GlaxoSmithKline
Biochemistry
Chemistry
CXC chemokine receptors
Bioavailability
Pharmacology
4
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40
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Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists
2018
Journal of Medicinal Chemistry
Hongfu Lu
Ting Yang
Zhongmiao Xu
Xichen Lin
Qian Ding
Yueting Zhang
Xin Cai
Kelly Dong
Sophie Gong
Wei Zhang
Metul Patel
Royston C. B. Copley
Jia-Ning Xiang
Xiaoming Guan
Paul Wren
Feng Ren
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Citations (9)
Discovery of CNS Penetrant CXCR2 Antagonists for the Potential Treatment of CNS Demyelinating Disorders.
2016
ACS Medicinal Chemistry Letters
Heng Xu
Hongfu Lu
Zhongmiao Xu
Linbo Luan
Chengyong Li
Yan Xu
Kelly Dong
Jinqiang Zhang
Xiong Li
Yvonne Li
Gentao Liu
Sophie Gong
Yonggang Zhao
Ailian Liu
Yueting Zhang
Wei Zhang
Xin Cai
Jia-Ning Xiang
John D. Elliott
Xichen Lin
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Citations (9)
2-Aminopyrimidin-4(1H)-one as the novel bioisostere of urea: Discovery of novel and potent CXCR2 antagonists
2014
Bioorganic & Medicinal Chemistry Letters
Hongfu Lu
Ting Yang
Zhongmiao Xu
Paul Wren
Yueting Zhang
Xin Cai
Metul Patel
Kelly Dong
Qing Zhang
Wei Zhang
Xiaoming Guan
Jia-Ning Xiang
John D. Elliott
Xichen Lin
Feng Ren
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Novel complex crystal structure of prolyl hydroxylase domain-containing protein 2 (PHD2): 2,8-Diazaspiro[4.5]decan-1-ones as potent, orally bioavailable PHD2 inhibitors
2013
Bioorganic & Medicinal Chemistry
Guanghui Deng
Baowei Zhao
Yingli Ma
Qiongfeng Xu
Hailong Wang
Liuqing Yang
Qing Zhang
Taylor B. Guo
Wei Zhang
Yang Jiao
Xin Cai
Jinqiang Zhang
Houfu Liu
Xiaoming Guan
Hongtao Lu
Jia-Ning Xiang
John D. Elliott
Xichen Lin
Feng Ren
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Citations (14)
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