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Edward Beck
Edward Beck
Janssen Pharmaceutica
Chemistry
Calcium channel
Biochemistry
Pharmacology
N-type calcium channel
5
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48
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Discovery and SAR of a novel series of 2,4,5,6-tetrahydrocyclopenta[c]pyrazoles as N-type calcium channel inhibitors.
2014
Bioorganic & Medicinal Chemistry Letters
Michael P. Winters
Nalin L. Subasinghe
Mark Wall
Edward Beck
Michael R. Brandt
Michael F.A. Finley
Yi Liu
Mary Lou Lubin
Michael P. Neeper
Ning Qin
Christopher M. Flores
Zhihua Sui
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Citations (6)
Discovery and SAR of novel tetrahydropyrrolo[3,4-c]pyrazoles as inhibitors of the N-type calcium channel
2014
Bioorganic & Medicinal Chemistry Letters
Michael P. Winters
Nalin L. Subasinghe
Mark Wall
Edward Beck
Michael R. Brandt
Michael F.A. Finley
Yi Liu
Mary Lou Lubin
Michael P. Neeper
Ning Qin
Christopher M. Flores
Zhihua Sui
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Citations (14)
Validation of a Patch Clamp Screening Protocol That Simultaneously Measures Compound Activity in Multiple States of the Voltage-Gated Sodium Channel Nav1.2
2011
Assay and Drug Development Technologies
Yi Liu
Edward Beck
Christopher M. Flores
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Citations (9)
An Integrated Multiassay Approach to the Discovery of Small-Molecule N-Type Voltage-Gated Calcium Channel Antagonists
2010
Assay and Drug Development Technologies
Michael F. A. Finley
Mary-Lou Lubin
Michael P. Neeper
Edward Beck
Yi Liu
Christopher M. Flores
Ning Qin
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Citations (9)
Development and Validation of a Secondary Screening Assay for TRPM8 Antagonists Using QPatch HT
2010
Assay and Drug Development Technologies
Edward Beck
Tasha Hutchinson
Ning Qin
Christopher M. Flores
Yi Liu
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Citations (10)
1