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Charles T. Jakubik

Harvard University

7

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361

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Abstract 1903: PTEN loss mediates clinical cross-resistance to CDK4/6 and PI3Ká inhibitors in breast cancer

2020 Cancer Research
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PTEN loss mediates clinical cross-resistance to CDK4/6 and PI3Kα inhibitors in breast cancer.

2019 Cancer Discovery
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Abstract 3431: PI3Kbeta regulates macropinocytosis in PTEN-null tumor cells

2019 Cancer Research
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Abstract 5502: Characterization of a hotspot PTEN mutation in endometrial cancer

2018 Cancer Research
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Exploitation of the Apoptosis-Primed State of MYCN-Amplified Neuroblastoma to Develop a Potent and Specific Targeted Therapy Combination

2016 Cancer Cell
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Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer

2015 Proceedings of the National Academy of Sciences of the United States of America
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Measurement of PIP3 Levels Reveals an Unexpected Role for p110β in Early Adaptive Responses to p110α-Specific Inhibitors in Luminal Breast Cancer

2015 Cancer Cell
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