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Stuart A. Lipton

Sanford-Burnham Institute for Medical Research
University of California, San Diego
Harvard University

515

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S-nitrosylated TDP-43 triggers aggregation, cell-to-cell spread, and neurotoxicity in hiPSCs and in vivo models of ALS/FTD.

2021 Proceedings of the National Academy of Sciences of the United States of America
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Protein S-Nitrosylation in Neuronal Development

2021
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Novel Therapeutic Approach for Excitatory/Inhibitory Imbalance in Neurodevelopmental and Neurodegenerative Diseases.

2021 Annual Review of Pharmacology and Toxicology
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Soluble α-synuclein-antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia.

2021 Proceedings of the National Academy of Sciences of the United States of America
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TCA cycle metabolic compromise due to an aberrant S-nitrosoproteome in HIV-associated neurocognitive disorder with methamphetamine use.

2021 Journal of NeuroVirology
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α-Synuclein Oligomers Induce Glutamate Release from Astrocytes and Excessive Extrasynaptic NMDAR Activity in Neurons, Thus Contributing to Synapse Loss.

2021 The Journal of Neuroscience
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Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation.

2021 Immunity
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Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases

2021 International Journal of Molecular Sciences
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Protein S-nitrosylation and oxidation contribute to protein misfolding in neurodegeneration.

2021 Free Radical Biology and Medicine
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Protein Transnitrosylation Signaling Networks Contribute to Inflammaging and Neurodegenerative Disorders

2021 Antioxidants & Redox Signaling
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Citations (4)