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Deborah R. Wysong

Millennium Pharmaceuticals

11

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1142

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MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors.

2015 ACS Medicinal Chemistry Letters
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Analysis of two pharmacodynamic biomarkers using acoustic micro magnetic particles on the ViBE bioanalyzer

2011 Analytical Biochemistry
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Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays

2011 Clinical Cancer Research
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The inhibition of Aurora A abrogates the mitotic delay induced by microtubule perturbing agents

2009 Cell Cycle
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289 POSTER Aurora A kinase inhibition abrogates the mitotic delay induced by microtubule perturbing agents

2008 Ejc Supplements
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MLN8237: an orally active small molecule inhibitor of Aurora A kinase in phase I clinical trials

2008 Cancer Research
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MLN8054, a Small-Molecule Inhibitor of Aurora A, Causes Spindle Pole and Chromosome Congression Defects Leading to Aneuploidy

2007 Molecular and Cellular Biology
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Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase

2007 Proceedings of the National Academy of Sciences of the United States of America
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MLN8054, an orally active Aurora A kinase small molecule inhibitor in phase I clinical trials

2006 Cancer Research
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Novel small-molecule inhibitors of RNA polymerase III

2003 Eukaryotic Cell
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Citations (63)