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Daniel Wettstein

Salk Institute for Biological Studies

21

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2240

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Timing of Liver Surgery with Curative Intent in the Multidisciplinary Treatment Of CRC

2020 Ejso
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A májtranszplantáció új kihívásai

2019 Orvosi Hetilap
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Discovery of an l-alanine ester prodrug of the Hsp90 inhibitor, MPC-3100

2015 Bioorganic & Medicinal Chemistry Letters
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Discovery of (2S)-1-[4-(2-{6-amino-8-[(6-bromo-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-9-yl}ethyl)piperidin-1-yl]-2-hydroxypropan-1-one (MPC-3100), a purine-based Hsp90 inhibitor.

2012 Journal of Medicinal Chemistry
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Characterization of the Cellular and Antitumor Effects of MPI-0479605, a Small-Molecule Inhibitor of the Mitotic Kinase Mps1

2011 Molecular Cancer Therapeutics
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Abstract 2617: MPC-3100, a synthetic Hsp90 inhibitor, induces biomarker changes in vitro and in vivo

2011 Cancer Research
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Abstract 3237: Evaluation of the pharmacokinetics and efficacy of a novel pro-drug of the HSP90 inhibitor, MPC-3100, designed with improved solubility

2011 Cancer Research
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Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT).

2011 Journal of Medicinal Chemistry
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Abstract 2628: Antitumor activity of MPC-3100, a synthetic Hsp90 inhibitor, in combination with erlotinib and sorafenib

2011 Cancer Research
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Abstract 3233: Comparative in vitro and in vivo metabolism of MPC-3100, an oral HSP90 inhibitor, in rat, dog, monkey and human

2011 Cancer Research
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