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Jerome Mettetal

AstraZeneca
Takeda Pharmaceutical Company

59

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2405

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A Systems Toxicology Approach for the Prediction of Kidney Toxicity and Its Mechanisms In Vitro

2019 Toxicological Sciences
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Using Quantitative Systems Toxicology to Investigate Observed Species Differences in CKA-Mediated Hepatotoxicity

2018 Toxicological Sciences
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Multiscale Mathematical Model of Drug-Induced Proximal Tubule Injury: Linking Urinary Biomarkers to Epithelial Cell Injury and Renal Dysfunction

2018 Toxicological Sciences
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Impact of a five-dimensional framework on R&D productivity at AstraZeneca

2018 Nature Reviews Drug Discovery
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Systems Pharmacology Model of Gastrointestinal Damage Predicts Species Differences and Optimizes Clinical Dosing Schedules

2018
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Information-Derived Mechanistic Hypotheses for Structural Cardiotoxicity

2018 Chemical Research in Toxicology
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Application of Microphysiological Systems to Enhance Safety Assessment in Drug Discovery

2018 Annual Review of Pharmacology and Toxicology
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Model‐Informed Reverse and Forward Translation of Safety Risks in Drug Development

2018 Clinical Pharmacology & Therapeutics
- Jerome Mettetal
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Understanding Hematological Toxicities Using Mathematical Modeling

2018 Clinical Pharmacology & Therapeutics
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Perspective on the State of Pharmacometrics and Systems Pharmacology Integration

2018
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Citations (7)