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Spencer C. Wei

University of Texas MD Anderson Cancer Center

18

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2597

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Checkpoint Blockade + Chemotherapy: the Right Combination for AML?

2021
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805 Clonal, activated CD8+ T cells recognizing cardiac alpha-myosin drive immune checkpoint inhibitor associated myocarditis in mice

2021 Journal for ImmunoTherapy of Cancer
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Combination of PD1 Inhibitor and OX40 Agonist Induces Tumor Rejection and Immune Memory in Mouse Models of Pancreatic Cancer.

2020 Gastroenterology
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A genetic mouse model recapitulates immune checkpoint inhibitor-associated myocarditis and supports a mechanism-based therapeutic intervention.

2020 Cancer Discovery
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Combination anti–CTLA-4 plus anti–PD-1 checkpoint blockade utilizes cellular mechanisms partially distinct from monotherapies

2019 Proceedings of the National Academy of Sciences of the United States of America
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Negative Co-stimulation Constrains T Cell Differentiation by Imposing Boundaries on Possible Cell States

2019 Immunity
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Fundamental Mechanisms of Immune Checkpoint Blockade Therapy.

2018 Cancer Discovery
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Negative costimulation constrains T cell differentiation

2018 Journal of Immunology
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Inhibition of Spinal 15-LOX-1 Attenuates TLR4-Dependent, NSAID-Unresponsive Hyperalgesia in Male Rats.

2018 Pain
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Inhibition of spinal 15-LOX-1 attenuates TLR4-dependent, nonsteroidal anti-inflammatory drug–unresponsive hyperalgesia in male rats

2018 Pain
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