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Chuin Lean Tham
Chuin Lean Tham
University College London
Chemistry
Biochemistry
Stereochemistry
Kinesin
Mitosis
5
Papers
33
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Eg5-inhibitor complex
2018
S. K. Talapatra
F. Kozielski
Chuin Lean Tham
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Design and synthesis of novel thiadiazole-thiazolone hybrids as potential inhibitors of the human mitotic kinesin Eg5
2018
Bioorganic & Medicinal Chemistry Letters
Samukelisiwe Pretty Khathi
Balakumar Chandrasekaran
Sivanandhan Karunanidhi
Chuin Lean Tham
Frank Kozielski
Nisar Sayyad
Rajshekhar Karpoormath
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Citations (5)
Ligand and structure based in silico studies to identify kinesin spindle protein (KSP) inhibitors as potential anticancer agents
2018
Journal of Biomolecular Structure & Dynamics
Chandrasekaran Balakumar
Muthusamy Ramesh
Chuin Lean Tham
Samukelisiwe Pretty Khathi
Frank Kozielski
Cherukupalli Srinivasulu
Girish A. Hampannavar
Nisar Sayyad
Mahmoud E. S. Soliman
Rajshekhar Karpoormath
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Citations (15)
Corrigendum to “Design and synthesis of novel thiadiazole-thiazolone hybrids as potential inhibitors of the human mitotic kinesin Eg5 [Bioorg Med Chem Lett 28 (17) (2018) 2930–2938]”
2018
Bioorganic & Medicinal Chemistry Letters
Samukelisiwe Pretty Khathi
Balakumar Chandrasekaran
Sivanandhan Karunanidhi
Chuin Lean Tham
Frank Kozielski
Nisar Sayyad
Rajshekhar Karpoormath
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Citations (1)
Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors.
2018
European Journal of Medicinal Chemistry
Sandeep K. Talapatra
Chuin Lean Tham
Paolo Guglielmi
Roberto Cirilli
Balakumar Chandrasekaran
Rajshekhar Karpoormath
Simone Carradori
Frank Kozielski
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Citations (12)
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