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Rik van der Kant

Netherlands Cancer Institute

23

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1787

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Cholesterol and Alzheimer's Disease; From Risk Genes to Pathological Effects.

2021 Frontiers in Aging Neuroscience
- Femke M. Feringa
- Rik van der Kant
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The probabilistic model of Alzheimer disease: the amyloid hypothesis revised.

2021 Nature Reviews Neuroscience
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Cholesterol Lowering Drugs Reduce APP Processing to Aβ by Inducing APP Dimerization.

2020 Molecular Biology of the Cell
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SKIP‐HOPS recruits TBC1D15 for a Rab7‐to‐Arl8b identity switch to control late endosome transport

2020 The EMBO Journal
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A high‐throughput drug screen identifies berberine as a potent inducer of tau clearance: Nonhuman/Target identification and validation studies: Tau

2020 Alzheimers & Dementia
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Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons

2019 Cell Stem Cell
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TARGETING ABERRANT CHOLESTEROL METABOLISM IN ALZHEIMER’S DISEASE: DRUG DISCOVERY IN IPSC-DERIVED NEURONS

2019 Alzheimers & Dementia
- Rik van der Kant
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Amyloid-β-independent regulators of tau pathology in Alzheimer disease

2019 Nature Reviews Neuroscience
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Defective Transcytosis of APP and Lipoproteins in Human iPSC-Derived Neurons with Familial Alzheimer’s Disease Mutations

2016 Cell Reports
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Cellular Functions of the Amyloid Precursor Protein from Development to Dementia

2015 Developmental Cell
- Rik van der Kant
- Lawrence S.B. Goldstein
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Citations (146)