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Leah DiMascio
Leah DiMascio
Medicine
Cancer research
Pembrolizumab
Immune system
Antibody
3
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HMBD-002 is a novel, neutralizing, anti-VISTA antibody exhibiting strong preclinical efficacy and safety, being developed as a monotherapy and in combination with pembrolizumab.
2021
Journal of Clinical Oncology
Leah DiMascio
Dipti Thakkar
Namita S. Gandhi
Guan Siyu
Eric K. Rowinsky
Ingram Piers
Boyd-Kirkup Jerome Douglas
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469 A phase 1 first in human study of HMBD-002, an IgG4 monoclonal antibody targeting VISTA, as a monotherapy and combined with pembrolizumab in patients with advanced solid malignancies
2021
Journal for ImmunoTherapy of Cancer
Leah DiMascio
Dipti Thakkar
Guan Siyu
Eric K. Rowinsky
Jordi Rodon
Joshua Gruber
Benjamin L. Musher
Joseph Kim
Alain C. Mita
Monica M. Mita
Ingram Piers
Boyd-Kirkup Jerome Douglas
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A phase 1 study to assess the safety, pharmacokinetics, and anti-tumor activity of the androgen receptor n-terminal domain inhibitor epi-506 in patients with metastatic castration-resistant prostate cancer.
2021
Investigational New Drugs
Corinne Maurice-Dror
Ronan Le Moigne
Ulka N. Vaishampayan
Robert B. Montgomery
Michael S. Gordon
Nan Hyung Hong
Leah DiMascio
Frank Perabo
Kim N. Chi
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