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Shimoga Prakash

Takeda Pharmaceutical Company

4

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33

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Preclinical Absorption, Distribution, Metabolism, Excretion, and Pharmacokinetics of A Novel Selective Inhibitor of Breast Cancer Resistance Protein (BCRP)

2018 Xenobiotica
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Absorption, Distribution, and Excretion of the Investigational Agent Orteronel (TAK-700) in Healthy Male Subjects: A Phase 1, Open-Label, Single-Dose Study.

2016 Clinical pharmacology in drug development
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Synthesis of a new inhibitor of breast cancer resistance protein with significantly improved pharmacokinetic profiles.

2016 Bioorganic & Medicinal Chemistry Letters
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Assessment of cytochrome P450-mediated drug–drug interaction potential of orteronel and exposure changes in patients with renal impairment using physiologically based pharmacokinetic modeling and simulation

2014 Biopharmaceutics & Drug Disposition
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Citations (23)