Postępująca wieloogniskowa leukoencefalopatia u pacjenta z chłoniakiem rozlanym z dużych limfocytów B i zespołem nabytego niedoboru odporności

Diffused large B-cell lymphoma (DLBCL) is an agressive and one of the most common lymphomas. The treatment of choice is R-CHOP (rituximab, cyclophosphamide, doxorubicine, vincristine, prednisone) immunochemotherapy. In some cases also radiotherapy is indicated. DLBCL and other non-Hodgkin lymphomas maybe an acquired immune deficiency syndrome defining condition in human immunodeficiency virus (HIV) infection, and therefore indication for testing for this virus. Not only HIV infection, but lymphoma as well as immunotherapy may lead to John Cunningham virus reactivation and development of the progressive multifocal leukoencephalopathy.