Sympathetic nervous response to ischemia-reperfusion injury in humans is altered with remote ischemic preconditioning

Muscle sympathetic nervous system (SNS) increases during forearm ischemia-reperfusion (IR) in healthy individuals. When remote ischemic preconditioning (RIPC) was applied before IR, the SNS response was delayed and attenuated, indicating that modulation of the SNS may play a role in the beneficial effects afforded by RIPC.