[PP.20.01] LCZ696 THERAPY IS ASSOCIATED WITH IMPROVEMENT OF VENTRICULAR ARTERIAL COUPLING AND WORK EFFICIENCY IN PATIENTS WITH HEART FAILURE AND REDUCED EJECTION FRACTION

Objective:Angiotensin receptor-neprilysin inhibition with LCZ696 is a novel approach for the treatment of heart failure with reduced ejection fraction (HFrEF). The aim of the study was to assess the effects of valsartan/sacubitril on parameters of ventricular-arterial coupling and left ventricular (