Antihypertensive Agents: Mechanisms of Drug Action

Hypertension is a major risk factor for the development of cardiovascular diseases. There is a direct relationship between blood pressure and the incidence of stroke and coronary events [1]. Even modest elevations in blood pressure (both systolic and diastolic) are associated with an increased health risk. Hypertension also predisposes to left ventricular hypertrophy and chronic renal failure [2, 3].