Abstract 12766: Perinatal Hypoxia Aggravates Occlusive Pulmonary Vasculopathy in the Adolescent Rats: Establishment of a Fatal Sugen/hypoxia Model and Its Molecular Basis

Hironori Oshita,Hirofumi Sawada,Yoshihide Mitani,Jane C. Kabwe,Noriko Yodoya,Naoki Tsuboya,Kazunobu Ohya,Hiroyuki Ohashi,Kazuo Maruyama,Masahiro Hirayama

Abstract 12766: Perinatal Hypoxia Aggravates Occlusive Pulmonary Vasculopathy in the Adolescent Rats: Establishment of a Fatal Sugen/hypoxia Model and Its Molecular Basis

2019

Hironori Oshita
Hirofumi Sawada
Yoshihide Mitani
Jane C. Kabwe
Noriko Yodoya
Naoki Tsuboya
Kazunobu Ohya
Hiroyuki Ohashi
Kazuo Maruyama
Masahiro Hirayama

Hypothesis: We tested the hypothesis that perinatal hypoxia, simulating fetal and neonatal distress, aggravates occlusive pulmonary vascular disease (PVD) in SUGEN/hypoxia (SuHx) rats. Methods: Per...

Keywords:

Cardiology
Internal medicine
Vascular disease
Hypoxia (medical)
Diabetes mellitus
pediatric cardiology
Fetus
Pulmonary hypertension
Perinatal hypoxia
Medicine

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