Abstract 18132: Prenatal Evaluation of the Fetal Cardiovascular Profile Score in a Multicenter Study of Ebstein Anomaly/Tricuspid Valve Dysplasia

Introduction: The cardiovascular profile (CVP) score is an echo based multivariable approach for assessment of fetal hemodynamics. The CVP score has been shown to be useful in predicting the outcome of fetuses with heart failure, growth restriction, and select congenital heart defects. The score ranges from 0 to 10, with points deducted for abnormal hemodynamics. In a previous pilot study of 21 fetuses with EA/TVD, a CVP score <7 was associated with poor outcomes. The aim of this study was to investigate the prognostic significance of the CVP score in a larger cohort of fetuses with EA/TVD. Methods: This 23-center study was a retrospective review of fetal echo data and outcomes in a cohort of 243 fetuses diagnosed with EA/TVD from 2005-2011. Both the first and last fetal echo in gestation were evaluated. Hydrops, heart size, cardiac function, and umbilical arterial and venous Dopplers were scored. The primary outcome was perinatal death, defined as fetal demise or death prior to neonatal discharge. Catego...