Keratinocyte-intrinsic BCL10/MALT1 activity initiates and amplifies psoriasiform skin inflammation.

Zsuzsanna Kurgyis,Larsen Vornholz,Konstanze Pechloff,Lajos Kemény,Tim Wartewig,Andreas Muschaweckh,Abhinav Joshi,Katja Kranen,Lara Hartjes,Sigrid M. C. Möckel,Katja Steiger,Erik Hameister,Thomas Volz,Mark Mellett,Lars E. French,Tilo Biedermann,Thomas Korn,Jürgen Ruland

Keratinocyte-intrinsic BCL10/MALT1 activity initiates and amplifies psoriasiform skin inflammation.

2021

Zsuzsanna Kurgyis
Larsen Vornholz
Konstanze Pechloff
Lajos Kemény
Tim Wartewig
Andreas Muschaweckh
Abhinav Joshi
Katja Kranen
Lara Hartjes
Sigrid M. C. Möckel
Katja Steiger
Erik Hameister
Thomas Volz
Mark Mellett
Lars E. French
Tilo Biedermann
Thomas Korn
Jürgen Ruland

Psoriasis is a chronic inflammatory skin disease arising from poorly defined pathological cross-talk between keratinocytes and the immune system. BCL10 (B cell lymphoma/leukemia 10) and MALT1 (muco...

Keywords:

Inflammation
Keratinocyte
Immune system
Leukemia
BCL10
Immunology
B-cell lymphoma
MALT1
Medicine
Psoriasis

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