CROI 2013: Advances in antiretroviral therapy.

Persaud and colleagues presented data describing a possible functional cure of an HIV-1–infected infant (Abstract 48LB). The infant was born to an HIVinfected mother who had not received prenatal care and was diagnosed with HIV-1 infection during delivery. The delivery was precipitous and no antiretroviral prophylaxis was given to the mother. The child was transferred to a tertiary medical center at 30 hours of age and was started on full treatment doses of zidovudine, lamivudine, and nevirapine. Initial testing showed that the mother had a preserved CD4+ cell count of 644/μL and a plasma HIV-1 RNA level of 2423 copies/mL. The infant had a plasma HIV-1 RNA level of 19,812 copies/mL and detectable HIV-1