Effect of oral supplementation of Aloe vera extract on haematology indices and immune cells of blood in rabbit

Aloe vera is being widely used in herbal medicine as antibacterial, antiviral, antifungal, and antiinflammatory agent. It is also used as topical application for many skin diseases; its antidiabetic effect in rats is also reported. Looking at its enormous medicinal effects, the present study was conducted to investigate the effects of oral supplements of Aloe vera extract on hemotology indices and immune cells of rabbit. Total of twenty (n=20) rabbits were selected and divided into 4 group’s i-e A, B, C and D with n=5 in each group. Group A was kept as control while B, C and D were given 400, 500 and 600 mg/kg of Aloe vera extract, respectively daily for 21 days. Blood samples were collected from central ear vein transferred into test tubes containing ethylene diamine tetra acetate (EDTA) on 0 day, 7th day, 14th day and 21st day and analysed for complete blood count (CBC). Results revealed that oral supplementation of A. vera extract significantly increase mean corpuscular haemoglobin (MCH), mean corpuscular volume (MCV) and lymphocytes at level (p< 0.05) and decrease neutrophils in normal domestic rabbits. Results of this study concluded that A. vera has hematopoetic and immunomodulatory effects; thus its extract can be used for the treatment of anemia and immune deficiency problems.