Intégration du pharmacien-clinicien dans l’optimisation thérapeutique des patients avec troubles neurocognitifs pris en charge en unité cognitivocomportementale Integration of the Clinical Pharmacist in the Optimisation of the Treatment of Patients with Neurocognitive Disorders, Cared for in a Cognitive Behavioural Unit

Purpose: The cognitive-behavioral units (UCC) are dedicated to Alzheimer’s disease patients with a worsening of behavior disorders. The aim is to describe pharmaceutical interventions performed by the clinical pharmacist during prescriptions analysis. Methodology: All patients hospitalized in the UCC (Hospices de Lyon, France) during 2011 were included. The clinical pharmacist performed prescription analysis and participated in multidisciplinary review. Results: Ninety-seven patients were included in the study. Among the 560 analyzed prescriptions, 190 pharmaceutical interventions were performed by clinical pharmacist and 148 were accepted (77.9%). Most frequently detected drug-related problems were nonconformity to guidelines or contraindication (39.9 %), dose adjustment (19.5%), and inappropriate administration route (17.6%). A substitution was proposed for 32% of pharmaceutical interventions. Conclusion: This study shows the impact of clinical pharmacist integrated to the multidisciplinary staff in order to improve drug prescribing and decrease iatrogenic risk in elderly.