Adult onset still's disease: Clinical features and course
1992
Fiftieen patients with adult onset Still's disease are described, all diagnosed according to recognized criteria. Mean delay in reaching a firm diagnosis was 16 months. Besides the typical clinical picture, there was a high frequency of pruriginous rash, one instance of overlapping polymyositis and recurrent systemic manifeistations in most cases. Chronic polyarticular involvement predominated, with radiological progression particularly in wrist, proximal interphalangeal and hip joints. However, functional prognosis at the end of mean 4.8-year course was satisfactory, as also the response to treatment maionly with steroid drugs and, on occasion, with remiting agent to alleviate arthritis.
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