Abstract 13259: IRX5 Transcription Factor Cooperate With TBX5/GATA4/NKX2-5 Complex to Regulate Several Human Cardiomyocyte Functions

Robin Canac,Bastien Cimarosti,Aurore Girardeau,Virginie Forest,Cynthia Fourgeux,Jeremie Poschmann,Guillaume Lamirault,Patricia Lemarchand,Nathalie Gaborit

Abstract 13259: IRX5 Transcription Factor Cooperate With TBX5/GATA4/NKX2-5 Complex to Regulate Several Human Cardiomyocyte Functions

2021

Robin Canac
Bastien Cimarosti
Aurore Girardeau
Virginie Forest
Cynthia Fourgeux
Jeremie Poschmann
Guillaume Lamirault
Patricia Lemarchand
Nathalie Gaborit

Introduction: The transcription factor (TF) Iroquois homeobox 5 (Irx5) is a key patterning and differentiation regulator. In humans, IRX5 regulates the expression of the main cardiac sodium ion cha...

Keywords:

Regulator
Homeobox
Gene expression
Epigenetics
GATA4
Stem cell
Transcription factor
Cell biology
Medicine

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