Abstract 10303: CRRL290: A Novel and Mechanism-Based Therapeutic Peptide Targeting the Crosstalk Between Angiotensin II and the Natriuretic Peptide System for Cardiorenal Disease

Xiao Ma,Seethalakshmi R. Iyer,Shawn Reginauld,Shuchong Pan,Ye Zheng,Valentina Cannone,Jeson Sangaralingham,John C. Burnett

Abstract 10303: CRRL290: A Novel and Mechanism-Based Therapeutic Peptide Targeting the Crosstalk Between Angiotensin II and the Natriuretic Peptide System for Cardiorenal Disease

2021

Xiao Ma
Seethalakshmi R. Iyer
Shawn Reginauld
Shuchong Pan
Ye Zheng
Valentina Cannone
Jeson Sangaralingham
John C. Burnett

Introduction: Therapeutic strategies dual-targeting renin-angiotensin system (RAS) and natriuretic peptide system (NPS), such as Sacubitril/Valsartan, have been proven promising in treating cardior...

Keywords:

mechanism based
Sacubitril
Peptide
Pharmacology
Crosstalk (biology)
Cardiorenal disease
Natriuretic peptide
Medicine
Angiotensin II
Valsartan

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