Erythrocyte sodium/lithium countertransport is associated with thrombotic and fibrinolytic factors in 58-year-old men

The metabolic syndrome, in which insulin resistance is the core feature, is associated both with dysregulation of thrombosis/ fibrinolysis and erythrocyte sodium/lithium countertransport (SLC).To investigate this further we designed a cross-sectional study to examine whether factors involved in coagulation- and fibrinolysis systems were associated with SLC independently of insulin resistance in 93 58-year-old men. SLC was in univariate analysis positively correlated with PAI-1 activity (r = 0.35, p