Uterine artery Doppler blood flow in cases of hydatidiform mole and its correlation with β-hCG

Abstract Objectives : To study the correlation between Doppler blood flow and β-human chorionic gonadotropin (hCG), to assess the course of the disease and the follow up evaluation. Setting : This study was conducted in Assiut University Hospital, Department of Obstetrics and Gynecology. Design : Longitudinal study. Subjects and methods : Fifteen cases of vesicular mole were recruited and followed up. The patients were evaluated the day before evacuation of the uterus. This included clinical assessment, Doppler uterine artery blood flow velocity waveforms using the Doppler indices and assessment of the serum level of β-hCG. These cases were followed up every 2 weeks in the first 2 months, and every month thereafter until the 6 month. Results : Twelve patients showed continuous decrease in β-hCG level from 1192±697 to 6±11IU/ml by the end of the second month. Systolic–diastolic (S/D) increased from (2.57±1.13) to (15.9±2.07) ( P P P r r r Conclusion : Doppler ultrasound can be used as an adjuvant tool in the follow up of cases of vesicular mole and can predict the progress in the course of the disease.