56: Non-invasive Respiratory Volume Monitoring To Develop A Risk Algorithm For The Safe Use Of Opioids

Introduction: Opioid-induced respiratory depression and post-operative apnea (POA) often lead to increased post-operative complications. Inadequate minute ventilation (MV) initiates the spiral of respiratory depression. MV monitoring can provide an early sign of respiratory decompensation. A novel, non-invasive Respiratory Volume Monitor (RVM) provides continuous, real-time respiratory volume traces and reports MV, tidal volume (TV) and respiratory rate (RR) in non-intubated patients. The utility of the RVM derived respiratory depression risk assessment algorithm to direct safe use of opioids, evaluate POA and improve PACU discharge decisions was evaluated. Methods: RVM data were collected from 114 PACU patients following elective orthopedic surgery. 50/114 of the patient’s received opioids. “Predicted” MV (MVPRED) and “Percent Predicted” (MVMEASURED /MVPRED x100%) was calculated for each patient using standard formulas. Prior to opioid administration patients were classified as: “Not-at-Risk”, MV>80% MVPRED and “At-Risk”, MV