Indoxyl sulfate associates with cardiovascular phenotype in children with chronic kidney disease

Johannes Holle,Uwe Querfeld,Marietta Kirchner,Alexandros Anninos,Jürgen G. Okun,Daniela Thurn-Valsassina,Aysun Karabay Bayazit,Ana Niemirska,Nur Canpolat,Ipek Kaplan Bulut,Ali Duzova,Ali Anarat,Rukshana Shroff,Yelda Bilginer,Salim Caliskan,Cengiz Candan,Jérôme Harambat,Zeynep Birsin Özcakar,Oguz Soylemezoglu,Sibylle Tschumi,Sandra Habbig,Ebru Yilmaz,Ayşe Balat,Aleksandra Zurowska,Nilgün Çakar,Birgitta Kranz,Pelin Ertan,Anette Melk,Karolis Azukaitis,Franz Schaefer

Indoxyl sulfate associates with cardiovascular phenotype in children with chronic kidney disease

2019

Background Cardiovascular disease is the leading cause of death in children with chronic kidney disease (CKD). Serum levels of gut-derived uremic toxins increase with deterioration of kidney function and are associated with cardiac comorbidities in adult CKD patients.

Keywords:

Medicine
Cause of death
Uremia
Disease
Renal function
Internal medicine
Gastroenterology
Diabetes mellitus
Endocrinology
Phenotype
Kidney disease
Indoxyl Sulfate
Uric acid
Nephrology
Comorbidity
Pulse wave velocity

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