FRI0723 Temporal patterns of sedentary behaviour and physical activity in patients with rheumatoid arthritis

Background Rheumatoid Arthritis (RA) is associated with increased risk of cardiovascular disease (CVD). Recent evidence suggests sedentary behaviour (waking behaviour ≤1.5 metabolic equivalents whilst sitting/lying) may contribute towards the progression of RA outcomes, including heightened CVD risk (1). Sedentary behaviour occupies the majority of waking hours among people with RA (1). However, the proportion of time spent sedentary is likely to fluctuate over the course of the day, with periods of high sedentarity representing more optimal opportunity for intervention, and thus potentially higher intervention efficacy. Objectives The aims of this study were; 1) to explore temporal patterns of sedentary behaviour (and physical activity) among RA patients, and 2) to examine associations between temporal sedentary patterns and predicted 10-year risk of CVD. Methods Patients with RA (N=97) wore a GT3X accelerometer for 7 days to assess habitual sedentary time ( Results Temporal patterns of sedentary time and PA are reported in Figure 1. Sedentary time declined throughout the morning (08:00–12:00). During the afternoon, sedentary time increased by 4.5 minutes (12:00–18:00; M =34.36±8.86 to M =39.06±7.91). A more marked increase in sedentary time was observed during leisure time (18:00–22:00; M =39.61±7.59 to M =47.90±6.30). Repeated measures analysis of variance (ANOVA) revealed sedentary time was significantly higher during leisure time (M =46.20±5.46) compared to the morning (M =36.88±5.61), and afternoon (M =38.50±6.07) [N =28, F(2,26)=43.48, p= Conclusions Interventions targeting leisure time sedentary behaviour (18:00–23:00), relative to more occupational sedentary behaviour (08:00–18:00), may offer the greatest potential for sedentary time reduction and associated improvements of CVD risk profile. Due to inverse patterns of engagement, replacing leisure time sedentary behaviour with light PA may offer an effective intervention approach. References Fenton SAM & Kitas GD. Rheumatoid Arthritis: Sedentary behaviour in RA – a new research agenda. Nat Rev Rheumatol 2016;12(12):698–700. Disclosure of Interest None declared