A Systemic Review: Structural Mechanism of SARS-CoV-2A and promising Preventive Cure by Phytochemicals

The novel corona virus 2019-nCoV has recently emerged as a human pathogen in the city of Wuhan in China’s Hubei province, causing fever, severe respiratory illness, and pneumonia disease recently named COVID-19 (1, 2). The world experienced the outbreaks of corona virus infection that threaten global pandemic in 2002-2003 by Severe Acute Respiratory Syndrome (SARS) and in 2011 by Middle East Respiratory Syndrome (MERS). The genomic sequence of SARS-CoV-2 showed similar, but distinct genome composition of SARS-CoV and MERS-CoV. Phytochemicals are a powerful group of compounds, belonging to secondary metabolites of plants and including a diverse range of chemical entities such as polyphenols, flavonoids, steroidal saponins, organ Sulphur compounds, and vitamins. The potential biological benefits such as antioxidant, anti-inflammatory, anticancer, antibacterial, antifungal and antiviral activities. The ideal technology would be vaccine that gives lifelong immunity with a single dose. When whole world community of scientist working hard to find out clinical solution of this problem so mean time we have to work with what we have in hand the best prevention approach and the phytonutrient could be a one of them.