SARCOPENIA EVALUATION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Aim: The aim of our study was to investigate changes in muscle mass with especially the comparison between people DM patients. Method: This randomized, prospective, controlled, single blind study was conducted in Physical medicine and Rehabilitation department of Bezm-i Alem Vakif University, faculty of Medicine. The patient group individuals taken from patients with type 2 diabetes mellitus. Healthy individuals were enrolled as the control group patients. A total of 126 patients completed the study (63 study group, 63 control group). The patients were between the ages of 40 and 65 included in this study. Body composition of the subjects was measured by Bioelectrical impedance analysis method. Muscle mass distribution of subjects with skeletal muscle index (SMI %):  Diabetic and nondiabetic patients evaluated with using total skeletal muscle mass (kg)/weight (kg) x100) formula. Results: A total of 126 patients completed the study (63 study group, 63 control group). The clinical and demographic characteristics of the patients and the healthy controls are listed in Table 1. The mean age was 59.31 ± 8.17 years. The mean disease duration was 11.42±2.82 years. The most important finding of our study in patients with type 2 diabetic SMI values were significantly lower than the control group. In addition, BMI, fat mass and fat percentage was significantly higher in type 2 diabetic patients. Conclusion: In conclusion, type 2 diabetes is associated with the excessive loss of skeletal muscle mass in older adults. Older adults with undiagnosed diabetes are at particularly high risk for the loss of skeletal muscle mass. Keywords: Sarcopenia, Type 2 Diabetes Mellitus, body muscle mass