IL-33/ST2 system: therapeutic target of ischemic stroke

Inflammation response is an important pathological process of neuronal cell death after stroke. Interleukin (IL) -33/ST2 system is involved in the inflammatory response process of ischemic stroke and has been proved to be a protective factor. This article reviews the role and mechanism of IL-33/ST2 system in the regulation of immune inflammation after ischemic stroke. Key words: Stroke; Brain Ischemia; Interleukin-33; Interleukin-1 Receptor-Like 1 Protein; Inflammation; Immunity