Ossifying Fibroma of The Cervical Spine: The First Case Report and Literature Review.

Abstract Background Ossifying fibroma (OF) is a benign tumor commonly occurring in the mandible and maxilla. Spinal involvement of OF is of great rarity. To the best of our knowledge, only three cases in the thoracic and lumbar spine had been reported. Methods We present a 22-year-old female with an OF of the atlas, which is the firstly described OF in cervical spine. The related literature was also reviewed. Results Only three spinal OFs involving the thoracic spine to sacrum have been reported. Here we present the first OF of the cervical spine. Conclusions Spinal involvement of OF is seldom. We report the first OF involving the cervical spine. Differential diagnosis of it from the primary spinal tumors should be included. OF occupies locally aggressive behaviors and high risk for recurrence. Complete resection, followed by regular follow up should be the ideal choice for treatment.