Aliskiren enhances protective effects of valsartan against type 2 diabetic nephropathy in mice

ObjectivesAddition of aliskiren, a direct renin inhibitor, to losartan provides additive reduction of urinary albumin excretion in type 2 diabetic patients. However, the detailed effect of aliskiren on type 2 diabetic nephropathy is still unknown. This study was undertaken to examine the efficacy of