Mn-based 2D layered nanomaterials for boosting the MRI signal

Abstract Manganese-based 2D nanoparticles with increased longitudinal relaxivity (r1) in MRI were synthesised by co-precipitation at low suprasaturation. The results of physico-chemical characterizations, i.e., XRD, FT-IR, DR UV-vis, N2 physisorption, and SEM, showed an excellent 2D nanomaterial in which manganese is predominantly incorporated as Mn2+ and Mn3+. The r1 relaxivity obtained on a 1.0 Tesla apparatus at pH = 7.4 is significantly improved (r1 = 1.298 mM-1 s-1) as compared with other similar layered materials containing manganese.