In Gastroesophageal Reflux Disease, Differential Gene Expression in the Duodenum Points Towards Enhanced Chylomicron Production and Secretion

Background Duodenal signaling affects esophageal motility and perception, both pathophysiological factors in gastroesophageal reflux disease (GERD). Duodenal gene expression abnormalities, contributing to altered esophageal sensorimotor function, have not been reported to date.