Rapid Hemorrhagic and Ischemic Stroke Evaluator (RHISE) - eScholarship

Introduction: Stroke: 5th leading cause of death and leading cause of long-term disability. Current diagnosis to distinguish between hemorrhagic and ischemic stroke with CT and MRI takes up to 6 hours. Project Goal: Design, build , and test first prototype of RHISE to detect distinguishing proteins present in early stages of stroke Solution Concept: ELISA immunoassay tests for: GFAP and NMDA NR2A GFAP: hemorrhagic stroke biomarker NMDA NR2A: ischemic stroke biomarker Faculty Adviser: Frithjof Kruggel, M.D., Ph.D., Department of Biomedical Engineering