Effects of Pharmaceutical Intervention on Perioperative Prophylactic Application of Antibiotics in Our Hospital

OBJECTIVE:To explore the effects of pharmaceutical intervention on intervention drug use during perioperative period,and to promote rational use of drugs in the clinic. METHODS:500 medical cases from Jul. to Dec. in 2011 were selected as non-intervention group;other 500 cases from Jan. to Jun. in 2012 were selected as intervention group in surgical department during perioperative period after the implementation of pharmaceutical intervention. The prophylactic application of antibiotics in 2 groups were analyzed. RESULTS:The utilization ratio of antibiotics in intervention group decreased from 84.80% to 29.60% ,mainly were first-generation cephalosporins;prophylactic drug use 0.5-2 h before operation increased from 77.59% to 94.59% ;and the other unreasonable drug use was significantly reduced,compared with non-intervention group. CONCLUSIONS:Perioperative pharmaceutical intervention is able to improve the consciousness of doctors to prescribe antibiotics reasonably and the level of rational drug use,significantly reduce the rate of perioperative prophylactic application of antibiotics,as well as shorten the treatment course of antibiotics.