Pharmacokinetics of Mirabegron, a β3-Adrenoceptor Agonist for Treatment of Overactive Bladder, in Healthy Japanese Male Subjects: Results from Single- and Multiple-Dose Studies

Hiromi Iitsuka,Tomoaki Tokuno,Yoko Amada,Hiroshi Matsushima,Masataka Katashima,Taiji Sawamoto,Shin Takusagawa,Marcel van Gelderen,Takanori Tanaka,Hideo Miyahara

Pharmacokinetics of Mirabegron, a β3-Adrenoceptor Agonist for Treatment of Overactive Bladder, in Healthy Japanese Male Subjects: Results from Single- and Multiple-Dose Studies

2014

Hiromi Iitsuka
Tomoaki Tokuno
Yoko Amada
Hiroshi Matsushima
Masataka Katashima
Taiji Sawamoto
Shin Takusagawa
Marcel van Gelderen
Takanori Tanaka
Hideo Miyahara

Background Mirabegron is a human β3-adrenoceptor agonist for the treatment of overactive bladder. The pharmacokinetic profile of mirabegron has been extensively characterized in healthy Caucasian subjects.

Keywords:

Diabetes mellitus
Overactive bladder
Urology
Mirabegron
Young adult
Agonist
Adrenergic receptor
Pharmacology
Medicine
Pharmacokinetics
multiple dose
healthy volunteers
β3 adrenoceptor agonist

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