The study of left ventricular pacing site and clinical benefit in heart failure patients with cardiac resynchronization therapy

Objective To investigate the relationship between different left ventricular pacing sites and clinical benefit in heart failure patients treated with cardiac resynchronization therapy (CRT). Methods Clinical data of 52 patients of CRT-P/D (pacing and defibrillation) implantation were collected. According to the left ventricular lead implantation sites, 52 cases were divided into anterior wall (10 cases), lateral wall (15 cases), posterior wall (16 cases), and posterior base group (11 cases). The efficacy of CRT was evaluated by Minnesota life quality score, left ventricular function and remodeling index. Results In addition to the anterior wall group, Minnesota life quality score of the other groups were significantly lower than preoperative group (P 0.05); the rest groups were lower than preoperative group (P 0.05). △QRSd was higher in side wall, posterior wall and posterior basal group after CRT implantation 3 months than anterior wall group (P<0.05), △QRSd in posterior basal group was lower than the other two groups (P<0.05). Conclusions Left ventricular electrode should be implanted at the side wall and posterior wall firstly, secondly at the posterior basal wall, and avoid at the anterior wall of the left ventricle. Key words: Heart failure/TH; Cardiac pacing, artificial